Divalproex Medication Information (dosing, side effects, patient counseling)

Your medication Divalproex

Divalproex sodium is also known by the brand name: Depakote, Depakote ER and Depakote Sprinkle capsules.

Divalproex sodium comes in 125, 250, and 500 mg tablets, 250 and 500mg extended release tablets, and 125mg sprinkle capsule.

Divalproex sodium is most commonly used to treat seizures, bipolar problems, and prevent migraine headaches. No matter what your doctor has you taking it for, divalproex sodium is taken by mouth with or without food 1 to 4 times a day. If upset stomach occurs, take divalproex sodium with food. If you miss a dose, take the missed dose as soon as you think about it. If it is close to time for your next dose, skip the missed dose and resume your normal dosing schedule. Do not take 2 doses at the same time or extra doses. For best results take each dose at the same time each day. Extended-release tablets must be swallowed whole, do not split or break tablets. Divalproex Sprinkle capsules may be swallowed whole or the capsule may be opened and sprinkled on small amount (1 teaspoonful) of soft food like pudding, or applesauce. This is to be used immediately (do not store or chew).

Some common side effects with divalproex sodium include headache, nausea, vomiting, diarrhea, tiredness, weakness, tremor, dizziness, blurry eye sight, and loss of hunger.
Some less common side effects include swelling of the arms or legs, high or low blood pressure, weight gain, and constipation.

Do not take divalproex sodium if: you are pregnant, have liver problems or under the age of 2 years.
This medication should not be abruptly discontinued because of the possibility of increasing seizure frequency.
While taking divalproex sodium, remember it is important to tell your doctor or pharmacist if:
• You have signs of an allergic reaction (rash, itching, swelling, tightness of the chest, etc.)
• You have dark urine, are feeling tired, are not hungry, have an upset stomach, are throwing up, or have yellowing of the skin or eyes.
• Are pregnant as this drug may cause very bad birth defects.
If you are or become pregnant and take this drug for seizures or bipolar disorder, talk to your doctor to see if you need to keep taking this drug.
All forms of divalproex sodium including the liquid needs to be stored at room temperature in a dry place away from children or pets.