Mubashir Hussain - Dye-Free Time-Resolved Laser Speckle Contrast Imaging for Blood Flow Assessment

Dr. Mubashir Hussain presented "Dye-Free Time-Resolved Laser Speckle Contrast Imaging for Blood Flow Assessment in Rat Skin Flaps" as part of the Postdoc Slam Competition during the University of Kentucky's 2025 Society of Postdoctoral Scholars Annual Research & Career Symposium.

Mubashir Hussain is a postdoctoral scholar at the Biomedical Optics Lab at the University of Kentucky. He has a background in electrical engineering and a PhD in biomedical engineering, focusing on developing optical instruments. His current research aims to improve non-invasive monitoring of tissue blood flow, particularly in surgeries like mastectomies and breast reconstruction. Using time-resolved laser speckle contrast imaging (TR-LSCI), he tracks blood flow in tissues without the need for dyes or contact sensors. Applied to a rat model, TR-LSCI accurately distinguishes healthy tissue from necrotic (dead) tissue by measuring changes in blood flow across different flap types. This non-invasive, dye-free technique offers a promising alternative to traditional methods, with the potential for better surgical decision-making and improved patient outcomes.