"What is Apoptosis?" The Apoptotic Pathways and the Caspase Cascade

This 3D medical animation explains the functioning of the extrinsic and intrinsic apoptotic pathways. We start off by taking a look at the important role apoptosis plays in growth and development as well as removing DNA damaged cells. Then we see how activation of the caspase cascade occurs in each external and internal signalling pathway. Lastly we get a glimpse of cancer cells and their ability to block apoptosis.

© Elvire Thouvenot-Nitzan, 2016
http://www.elvirethouvenot.com

This resource is shared under Attribution-NonCommercial-NoDerivatives Creative Commons license (CC-BY-NC-ND 4.0). You are free to copy and reuse this for non-commercial purposes but we ask that you acknowledge “Elvire Thouvenot-Nitzan, created in collaboration with University of Dundee” when doing so. If you remix or modify this material, you may not distribute the modified material.

Medical Animator
Elvire Thouvenot-Nitzan BSc, MSc
Centre for Anatomy and Human Identification, University of Dundee

Medical Advisor and Pathology Instructor
Richard Oparka MBChB, FRCPath
Department of Histopathology, University of Dundee School of Medicine

MSc Medical Art Advisor
Caroline Erolin BA(Hons), PGCert, MPhil
Centre for Anatomy and Human Identification, University of Dundee

Technical Advisor
Annie Campbell BSc, MSc
Technology & Innovation Learning Team, University of Dundee School of Medicine

Attributions:

This animation features the track “Enrichment” by Podington Bear. The track is licensed under CC BY-NC 3.0 and has been edited to fit the animated short.
freemusicarchive.org/music/Podington_Bear/Backbeat/Enrichment

The animation features sound effects from freesfx.co.uk.