Vitamin B5 (Pantothenic Acid) - usmle Quick review

📌𝐅𝐨𝐥𝐥𝐨𝐰 𝐨𝐧 𝐈𝐧𝐬𝐭𝐚𝐠𝐫𝐚𝐦 :-   / drgbhanuprakash  

Functions
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Essential component of coenzyme A (pantothenic acid + ADP + cysteine)
Cofactor for the transfer of acyl groups → activation of carboxylic acids (e.g., pyruvate dehydrogenase, α-ketoglutarate dehydrogenase)
Cofactor for fatty acid, cholesterol, and acetylcholine synthesis

Vitamin B5 deficiency
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Clinical features
1.Adrenal insufficiency; may lead to distal paresthesias and dysesthesias (burning sensation of the feet)
2.Alopecia
3.Dermatitis
4.Enteritis
Vitamin B5 is pentothenic acid, as in “penta,” the Greek word for “five.”

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