Simulating the Evolution of Aging

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Ageless book: https://ageless.link/
Andrew Steele on YT:    / @drandrewsteele  

Papers and other further reading:
Diversity of aging across the tree of life: https://pmc.ncbi.nlm.nih.gov/articles...
Antagonistic pleiotropy and p53: https://pmc.ncbi.nlm.nih.gov/articles...
An unsolved problem of biology (Medawar): https://ia903408.us.archive.org/31/it...
Evolution of the mutation rate: https://pmc.ncbi.nlm.nih.gov/articles...
Our World in Data Life Expectancy explainer: https://ourworldindata.org/life-expec...

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00:00 Introduction and outline
00:43 In which I beg for money
03:05 Simulation rules
04:09 Analyzing lifespans with no aging
09:19 Simple death genes
14:43 Mutation accumulation
26:58 Antagonistic pleiotropy
29:59 Review
30:21 Recommendations

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