Allodynia, Central Sensitization, and the Progression of Migraine

Episode 225: Why can something as simple as wearing earrings or taking a shower trigger pain when living with migraine?

In this episode of HeadWise, Lindsay Weitzel, PhD, is joined by leading headache specialist Dr. Richard Lipton to explore the phenomenon of allodynia—when normally non-painful touch becomes painful. They break down how this symptom develops through central and peripheral sensitization, why it can signal migraine progression, and how early treatment may help reverse it.

You’ll also learn:
What allodynia feels like
How to tell if you have it (and why it matters)
Which medications help—or hurt—when allodynia is present
Why pain in other parts of the body often travels with migraine

#Allodynia #MigraineAwareness #ChronicMigraine #InvisibleIllness #PainScience #CentralSensitization #Neurology
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Chapters
[00:00] Meet Dr. Richard Lipton
[00:48] What Is Allodynia?
[02:18] How the Brain Becomes Sensitive to Pain
[04:09] Central vs. Peripheral Sensitization
[06:34] How Common Is Allodynia in Migraine?
[06:52] Why Early Treatment Matters
[10:20] Medications That Help or Harm
[13:46] How to Know If You Have Allodynia
[15:26] Acute vs. Preventive Treatments
[18:31] When Allodynia Spreads Beyond the Head
[21:39] Migraine and Other Chronic Pain Conditions
[25:27] Is Allodynia Reversible?
[28:55] Breaking the Pain Cycle
[31:34] Final Thoughts and Hope
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Follow the National Headache Foundation's podcast HeadWise, as host Lindsay Weitzel, PhD, has informative discussions with headache experts on the latest treatment, research, lifestyle recommendations, and personal stories about living with migraine disease and headache disorders. HeadWise can be found on Apple Podcasts, Spotify, Stitcher, Overcast, or wherever you get your podcasts.

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