25-08 Matt Cooperberg, MD MPH "Prostate Cancer 2025: Screening, Active Surveillance & Focal Therapy"

What’s new in prostate cancer care in 2025? Dr. Matt Cooperberg of UCSF shares the latest updates on screening, active surveillance, focal therapy, and treatment decision-making. An essential talk for patients, caregivers, and clinicians looking to understand risk, avoid overtreatment, and benefit from the newest advances.


00:00 Introduction & About Dr. Matt Cooperberg (UCSF)
00:55 Prostate Cancer Today: Screening, Incidence & Mortality
15:45 Active Surveillance vs Watchful Waiting — Who Qualifies?
32:30 Focal Therapy Explained: HIFU, Cryotherapy & Beyond
38:56 Key Takeaways & Audience Q&A

Key highlights include:
• 📊 Screening trends: How PSA guidelines have swung over time, the risks of over- and under-diagnosis, and why smarter screening is critical.
• ⚖️ Risk stratification: Understanding the spectrum from indolent “snails” to aggressive “rabbits,” and how tools like the CAPRA score improve decision-making beyond traditional NCCN categories.
• 👀 Active surveillance: Why surveillance—not immediate treatment—is the standard of care for most low-risk cancers, and how MRI, confirmatory biopsies, and genomic tests refine monitoring.
• 🔬 Focal therapy: The promise and limits of approaches like HIFU, cryotherapy, and laser ablation, and why they should be viewed as complements to surveillance rather than replacements for surgery or radiation.
• 🧪 Genomic and AI testing: Where tools like Decipher, Polaris, and emerging pathology AI fit in—and where they don’t—when guiding patient choices.
• 🏥 Second opinions & centers of excellence: Why outcomes vary widely, and the importance of seeking subspecialist expertise before choosing a treatment path.

Dr. Cooperberg also emphasizes the urgent need to reduce racial disparities, personalize treatment decisions, and support men living with prostate cancer long after initial therapy.

👉 Whether you are newly diagnosed, considering active surveillance, or exploring focal therapies, this talk offers practical, evidence-based insights into today’s rapidly evolving prostate cancer landscape.

==== About the Prostate Forum ======
📌 About the Prostate Forum of Orange County
The Prostate Forum of Orange County (PFOC) is a nonprofit, volunteer-run support and education group for men and their families affected by prostate cancer. We host online support groups on the 2nd and 4th Tuesdays of each month, and feature presentations from medical experts on the 4th Thursday of most months. Our goal is to provide reliable information, expert insight, and a welcoming community where patients, survivors, and caregivers can share experiences and learn together.

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⚠️ Disclaimer
The information presented in this video is for educational purposes only. It is not medical advice. Always consult your healthcare provider before making treatment decisions.

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