Understanding Embryo Grading & Blastocyst Grades | What do embryo grades mean? CACRM

Dr. Lori Arnold talks about embryo grading in detail in this informative video about understanding embryo grading & blastocyst grades.
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This video is presenting understanding embryo grading & blastocyst grades and success rates valuable information but also try to cover the following subject:
-Understanding Embryo Grading & Blastocyst Grades
-Embryo grading
-Blastocyst
-Pregnancy success rates

Embryo grading is a tool that helps embryologists and physicians during an IVF treatment to determine, exactly which embryos to transfer, the optimal day of transfer, and the appropriate number of embryos to transfer. Typically done on Day 3 and Day 5, grading is not used independently, but is used along with a patient’s age, fertility history, and other information for deciding the optimum embryo(s) to transfer. Grading only refers to the “appearance of the embryo” and as individual judgment is important, this is a highly subjective assessment. At GENESIS, all assessments are done on inverted microscopes; using CAP proficiency testing 3 times a year to verify accurate embryo quality assessment.

Day 3 Embryos:
Day 3 (D3) embryos are referred to as “cleavage stage embryos”. This means they are dividing (or cleaving) but the embryo itself is not growing in size. They typically consist of 6-8 cells inside an outer covering called the zona pellucida; also known as the shell. GENESIS uses cell numbers and degrees of fragmentation to assess the quality of D3 embryos. Typically an 8A on D3 is the best grade.

Grade A:
These embryos show that there are 6-8 evenly sized cells, with no or less than 10% fragmentation.

Grade B:
These embryos have more uneven or irregularly shaped cells with 25-50% fragmentation.

Grade C:
These embryos show 50% or more fragmentation.


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