Kidney Stones With Chlorthalidone Versus Hydrochlorothiazide

#nkfclinicals #nephrology #kidneystone #diuretics
Areef Ishani, MD, is director of the primary and specialty care service line at the Minneapolis Veterans Affairs (VA) Health Care System and acting director of the VA Midwest Health Care Network (Veterans Integrated Services Networks 23) specialty care integrated care community. His late-breaking abstract at the National Kidney Foundation Spring Clinical Meetings 2025 (SCM25) compared chlorthalidone and hydrochlorothiazide for the prevention of kidney stones.

The results came from a secondary analysis from the Diuretic Comparison Project, a national study comparing the effects of the two thiazide-type diuretics on cardiovascular outcomes in older US veterans with hypertension. Joel Topf, MD, spoke with Dr. Ishani about kidney outcomes at SCM24 in Long Beach, California, and the two met again at SCM25 in Boston, Massachusetts, to discuss the kidney stone outcomes.