Polycystic Ovary Syndrome | Women's Health

In this episode, we are joined by Sun Kim, MD, MS, Associate Professor Medicine - Endocrinology, specializing in the management of type 2 diabetes, polycystic ovarian syndrome (PCOS), and obesity. PCOS affects an estimated 8–13% of women of reproductive age and is leading factor in infertility. Dr. Kim will review the diagnostic criteria for PCOS and discuss the contributing factors associated with this condition. We will review the various manifestations and comorbidities that accompany PCOS. During the discussion, Dr. Kim will cover topics including the impact of insulin resistance, the role of lifestyle modifications, available treatment approaches, fertility interventions, and indications for specialty care for patients with PCOS.

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Key moments:
00:00 Introduction to Women's Health Vodcast series
01:02 What led you to specialize in endocrinology, specifically Polycycstic Ovarian Syndrome (PCOS)?
03:30 Defining PCOS
05:25 What do we currently know about the pathophysiology of PCOS?
09:10 What are some symptoms or presentations that primary care providers might miss as PCOS patients?
12:40 Utilizing menstruation as a vital sign
13:55 Rotterdam criteria (Ovulatory dysfunction, hyperandrogenism, & hair loss)
20:50 Ultrasound criteria and PCOS implications
24:30 Excluding other diagnoses (primary ovarian insufficiency, hypogonadotropic hypogonadism, hypercortisolism, etc.)
28:35 Does time of day matter for lab tests?
29:57 Cushing's syndrome
31:20 Will dexamethasone affect any tests?
33:00 Insulin resistance
38:40 Current role of metformin, lifestyle guidelines for insulin resistant patients
45:20 Considerations for patients who want to conceive
48:50 Racial/ethnic differences
53:20 Birth control
58:20 Long term health risks of PCOS
01:01:10 Key takeaways