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Acanthosis Nigricans Explained | Early Sign of Insulin Resistance & Diabetes | Endocrinologist Insight

Dark patches on the neck, underarms, or knuckles are often ignored as a cosmetic issue—but medically, they can be a warning sign of insulin resistance.

In this video, I explain Acanthosis Nigricans from an endocrinology and metabolic health perspective:

What acanthosis nigricans really is

Why it develops (the role of insulin resistance and high insulin levels)

Its connection to prediabetes, type 2 diabetes, obesity, PCOS, and metabolic syndrome

When it can signal serious underlying conditions

Evidence-based treatment approaches that actually work

⚠️ Important: Creams alone cannot cure acanthosis nigricans. The key is correcting the root metabolic cause.

This video is especially useful for:

People with dark neck pigmentation

Individuals with overweight, diabetes, or PCOS

Anyone concerned about insulin resistance and cardiometabolic risk

👨‍⚕️ Presented by:
Nutritionist Hiroshan Jayaranga
Medical Council–Registered Nutritionist
Founder – Nutri Info Sri Lanka

📌 Educational content only. Always consult a qualified healthcare professional for diagnosis and treatment.

📚 Research References (Evidence-Based)

Burke JP, Hale DE, Hazuda HP, Stern MP.
A quantitative scale of acanthosis nigricans.
Diabetes Care. 1999;22(10):1655–1659.

Stuart CA, Pate CJ, Peters EJ.
Prevalence of acanthosis nigricans in an unselected population.
American Journal of Medicine. 1989;87(3):269–272.

Hud JA, Cohen JB, Wagner JM, Cruz PD.
Prevalence and significance of acanthosis nigricans in adults.
Journal of the American Academy of Dermatology. 1992;27(4):507–513.

American Diabetes Association.
Standards of Medical Care in Diabetes.
Diabetes Care. Updated annually.

Kahn CR, Flier JS.
Obesity and insulin resistance.
Journal of Clinical Investigation. 2000;106(4):473–481.

Phiske MM.
An approach to acanthosis nigricans.
Indian Dermatology Online Journal. 2014;5(3):239–249.

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