4-Step Protocol to Treat Histamine Intolerance (Best Diet & Supplements)

We’ve worked with many patients who struggle with histamine intolerance, and over years of research and experience, we’ve compiled the most effective treatment methods! In this episode, I’ll walk you through the 4-step protocol that we’ve developed that will help you heal from histamine intolerance.

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And if you have any questions or topics you would like covered in the future, let me know in the comments!

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Timestamps
00:00 Intro
00:38 Symptoms & causes
06:10 Diet
13:54 Gut microbiota modulation
20:54 Antihistamines & MC stabilizers
24:00 Nutrients for metabolism
26:08 Other considerations

Featured Studies
📉The dietary treatment of histamine intolerance reduces the abundance of some histamine-secreting bacteria:
https://pubmed.ncbi.nlm.nih.gov/36337...
📉Histamine Intolerance: The Current State of the Art:
https://pubmed.ncbi.nlm.nih.gov/32824...
📉High FODMAP diet causes barrier loss via lipopolysaccharide-mediated mast cell activation:
https://pubmed.ncbi.nlm.nih.gov/34618...
📉Effect of Candida albicans plus histamine on prostaglandin E2 production by peripheral blood mononuclear cells: https://pubmed.ncbi.nlm.nih.gov/1906913/
📉Candida-induced histamine release from basophils: https://pubmed.ncbi.nlm.nih.gov/2411109/
📉What to know about Candida when you have Mast Cell Activation Syndrome | Histamine Intolerance:
https://mastcell360.com/what-to-know-...
📉Effects of probiotics administration on lactose intolerance in adulthood:
https://pubmed.ncbi.nlm.nih.gov/37225...
📉The Efficacy and Safety of Probiotics for Allergic Rhinitis:
https://pubmed.ncbi.nlm.nih.gov/35663...
📉In vitro assessment of histamine and lactate production by a multi-strain synbiotic:
https://pubmed.ncbi.nlm.nih.gov/35875...
📉Effects of Dietary Components on Mast Cells: Possible Use as Nutraceuticals for Allergies?:
https://pubmed.ncbi.nlm.nih.gov/37998...
📉Luteolin Is More Potent than Cromolyn in Their Ability to Inhibit Mediator Release from Cultured Human Mast Cells: https://pubmed.ncbi.nlm.nih.gov/38588...
📉Melatonin reduces exo-endocytosis in mast cells:
https://pubmed.ncbi.nlm.nih.gov/37557...
📉Antihistamine effect of supplemental ascorbic acid and neutrophil chemotaxis:
https://pubmed.ncbi.nlm.nih.gov/1578094/
📉Histamine intolerance: lack of reproducibility of single symptoms by oral provocation with histamine:
https://pubmed.ncbi.nlm.nih.gov/21165...
📉Diamine Oxidase Supplementation in Chronic Spontaneous Urticaria:
https://pubmed.ncbi.nlm.nih.gov/29698...
📉Diamine oxidase (DAO) supplement reduces headache in episodic migraine patients:
https://pubmed.ncbi.nlm.nih.gov/29475...
📉Exogenous Supplementation with DAO Enzyme in Women with Fibromyalgia:
https://pubmed.ncbi.nlm.nih.gov/37892...
📉Histamine Intolerance-The More We Know the Less We Know:
https://pubmed.ncbi.nlm.nih.gov/34209...
📉Effect of the menstrual cycle on serum diamine oxidase levels in healthy women:
https://pubmed.ncbi.nlm.nih.gov/23099...
📉The impact of psychological stress on mast cells:
https://pubmed.ncbi.nlm.nih.gov/32687...
📉Chemical Intolerance and Mast Cell Activation:
https://pubmed.ncbi.nlm.nih.gov/37987...
📉The impact of psychological stress on mast cells:
https://pubmed.ncbi.nlm.nih.gov/32687...

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DISCLAIMER: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment or discontinuing an existing treatment.

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