How to Configure Outbound Spam Policies in Microsoft Defender for Office 365

Microsoft Defender for Office 365: Outbound Spam Policy & Exchange Online Protection Guide
Welcome to our comprehensive deep dive into configuring and optimizing Microsoft Defender for Office 365’s Outbound Spam Policies and Exchange Online Protection (EOP)! Whether you're an IT admin, cybersecurity analyst, or Microsoft 365 enthusiast, this video gives you everything you need to stop outbound spam in its tracks, protect your organization’s reputation, and keep your users secure.
What You'll Learn in This Video:
What is Outbound Spam and Why It Matters
The Role of Microsoft Defender in Email Security
How Exchange Online Protection Identifies and Handles Outbound Spam
Creating and Applying Outbound Spam Policies in Microsoft 365 Defender Portal
Real-World Use Cases and Configuration Scenarios
Tips to Reduce False Positives and Maintain Delivery Reliability
Admin Tools for Monitoring and Reporting Suspicious Activity
Best Practices for Policy Management and Continuous Improvement
About Outbound Spam in Microsoft 365
Outbound spam can seriously impact your organization's credibility, resulting in blacklisting, email delivery failures, and reputational damage. With hybrid and cloud-native environments becoming the norm, Microsoft Defender for Office 365 offers sophisticated capabilities to monitor and mitigate these threats before they leave your tenant.
In this video, we demonstrate step-by-step how to identify, configure, and fine-tune outbound spam policies to ensure only legitimate communication is leaving your system—without throttling performance or losing critical messages to misclassification
Featured Tools & Interfaces:
Microsoft 365 Defender Portal
Security & Compliance Center
PowerShell (Optional for Advanced Configs)
Threat Explorer & Audit Logs
Message Trace in Microsoft Purview
Configuration Tips:
Always define a clear outbound spam policy with logging enabled.
Use Transport Rules for added granularity on sensitive departments.
Enable auto-forwarding restrictions to mitigate misuse.
Regularly audit compromised accounts using Threat Explorer.
Monitor sender reputation and volume to avoid automatic throttling.