Journal Club: The Rise of Fatty Liver Disease and its Metabolic Roots | Ep.66

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In today's journal club episode, co-hosts of The Metabolic Link, Dr. Angela Poff and Dr. Dominic D'Agostino, unpack the startling rise of non-alcoholic fatty liver disease (NAFLD)—a silent epidemic affecting millions worldwide. Tune in as they break down groundbreaking new research revealing how NAFLD isn't just impacting adults, but alarmingly, children and adolescents too.

You'll learn about the latest updates in terminology, such as Metabolic Dysfunction Associated Steatohepatitis (MASH) and Metabolic Dysfunction Associated Steatotic Fatty Liver Disease (MASLD), highlighting a critical connection to underlying metabolic dysfunction. Plus, discover exciting dietary strategies—like therapeutic carbohydrate restriction—that hold potential not just to prevent, but to actually reverse liver fat accumulation.

If you've ever wondered how your diet and lifestyle choices directly shape your metabolic health, this episode delivers practical insights and actionable information straight from cutting-edge science. Don't miss this deep dive into the latest science on NAFLD—and how simple shifts today could dramatically improve your metabolic health tomorrow.

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Read the papers discussed in the episode here:
The Global Epidemiology of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis Among Patients With Type 2 Diabetes: https://pubmed.ncbi.nlm.nih.gov/38521...
The impact of short-term eucaloric low- and high-carbohydrate diets on liver triacylglycerol content in males with overweight and obesity: a randomized crossover study: https://pubmed.ncbi.nlm.nih.gov/38914...
Prevalence of nonalcoholic fatty liver disease in pediatrics and adolescents: a systematic review and meta-analysis: https://pubmed.ncbi.nlm.nih.gov/38771...
Ketogenic diet time-dependently prevents NAFLD through upregulating the expression of antioxidant protein metallothionein-2: https://pubmed.ncbi.nlm.nih.gov/38723...

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Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.