Best Practices for PROTACs - Assays and Cooperativity (Part 1B)
Автор: European Federation for Medicinal Chemistry
Загружено: 2024-11-21
Просмотров: 952
In part 1B we describe commonly used assays for assessing and optimization of PROTACs. We discuss the importance of the formation of a ternary complex and explain the term “cooperativity.” A workflow from industry is shown to illustrate PROTAC optimization.
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