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Gene Set Enrichment Analysis (+ R tutorial)

RNA-Seq analysis

DEGs analysis

GSEA

ORA

gene annotation

Автор: LiquidBrain Bioinformatics

Загружено: 7 авг. 2021 г.

Просмотров: 55 643 просмотра

Описание:

Enrichment analysis is very common in the Omics study. Did you know, with the same result from the Differential Expression Analysis, we can obtain two different types of enrichment results. This video guides you on the how and why performing them.

Apologize for the bad audio background

Useful links:
1. ClusterProfiler tutorial book
http://yulab-smu.top/clusterProfiler-...
2. Harvard Chan Bioinformatics Core (HBC) learning hub
https://hbctraining.github.io/DGE_wor...
3. GSEA original paper
Subramanian, A., Tamayo, P., Mootha, V. K., Mukherjee, S., Ebert, B. L., Gillette, M. A., ... & Mesirov, J. P. (2005). Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proceedings of the National Academy of Sciences, 102(43), 15545-15550.

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