A Fascinating Compound for Health​ - Palmitoylethanolamide (PEA) | The Microbiome Expert

PEA (Palmitoylethanolamide): A Powerful Ally for Inflammation, Pain & Brain Health The Microbiome Expert
Welcome to my deep dive on Palmitoylethanolamide (PEA)—a fascinating and underutilized fatty acid amide with incredible potential for supporting chronic pain, inflammation, mast cell activation, neurodegenerative conditions, and more. If you’ve tried probiotics, thiamine, zinc, or magnesium with limited success, this video may shift your perspective toward something that works with your biology—not against it.
PEA is naturally produced by your body in response to stress and inflammation, but chronic dysregulation can deplete this powerful molecule. I’ll explain how PEA works by activating PPAR-alpha and supporting the endocannabinoid system, indirectly influencing receptors like CB2 and TRPV1, and downregulating excessive mast cell and microglial activation—key players in chronic pain, anxiety, gut issues, and brain fog.
What You'll Learn:
How PEA works on PPAR-alpha, mast cells, and brain immune cells
Its role in reducing inflammation and restoring homeostasis
Why PEA supports people with pain, fatigue, anxiety, dysbiosis, migraines, and depression
Human research supporting its effectiveness—faster than you might think
When to consider micronized PEA forms for better brain penetration
If you’re struggling with inflammation or neurological symptoms, PEA may be a game-changer in your health protocol—without side effects and without hype.
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