The evolving story of PCSK9 - Weekly Research Conference with Thomas Lagace, PhD

A secreted protein with roles in cholesterol homeostasis and innate immunity

PCSK9 promotes degradation of liver LDL receptors, raising blood LDL-cholesterol and related cardiovascular risk. Therapeutic PCSK9 inhibition has revealed an unanticipated role in inflammation and innate immunity.

Speaker:
Thomas Lagace, PhD
Scientist & Director
Lipoprotein Receptor Biology Laboratory, UOHI

Associate Professor
Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa