The Role of N-Nitrosamines and Microcystin in Esophageal Cancer Progression | Mingjun Sun

In this advanced presentation, Mingjun Sun from Southeast University, China, explores the molecular mechanisms by which N-nitrosamines combined with microcystin promote the malignant transformation of esophageal epithelial cells. The study specifically investigates how these environmental toxins mediate the downregulation of Hsa_circ_0006867, activating the miR-499a-3p/MEF2C signaling pathway to drive carcinogenesis.

The research reveals that the interplay between chemical exposures and non-coding RNA regulation contributes to esophageal tumor initiation and progression. By elucidating this pathway, Mingjun highlights potential biomarkers for early detection and therapeutic targets for intervention in esophageal cancer. The presentation underscores the critical role of environmental carcinogens and molecular signaling in shaping cancer risk.

This session provides attendees with:
🧬 Insights into Hsa_circ_0006867 and miR-499a-3p/MEF2C signaling in esophageal carcinogenesis
🔬 Evidence on the synergistic effects of N-nitrosamines and microcystin on epithelial transformation
💡 Potential biomarkers and therapeutic targets for esophageal cancer
🌱 Implications for early detection, prevention, and translational oncology research
👩‍⚕️ Guidance for researchers and clinicians exploring molecular mechanisms of toxin-induced cancers

A valuable session for molecular biologists, oncologists, toxicologists, and researchers focused on esophageal cancer, non-coding RNA regulation, and environmental carcinogenesis.

5th Edition World Nursing and Healthcare Summit (WNHS2024)

📅 23–25 September 2024
📍 Village Hotel Changi, Singapore
🌐 Hosted by Scholars Conferences

For more details, visit the official website:
🔗 https://scholarsconferences.com/nursi...

#EsophagealCancer #CircRNA #miR499a3p #MEF2C #EnvironmentalCarcinogens #NNitrosamines #Microcystin #MolecularOncology #CancerMechanisms #ToxinInducedCancer #Biomarkers #TranslationalResearch