Deciphering T cell heterogeneity in humans through analysis of antigen-specificity
Автор: Labroots
Загружено: 2020-12-27
Просмотров: 319
Presented By: Evan Newell, PhD
Speaker Biography: Evan Newell is an Associate Professor in the Vaccine and Infectious Disease Division at the Fred Hutchinson Cancer Research Center. He completed his BSc in immunology at McGill University and PhD in physiology at the University of Toronto. As a postdoc at Stanford University with Mark Davis he worked on biophysical aspects of T cell antigen recognition and initiated the use of mass cytometry for the study of human T cell responses.
Webinar: Deciphering T cell heterogeneity in humans through analysis of antigen-specificity
Webinar Abstract: In line with the role of T cells as critical mediators of the adaptive immune response, recombinational and junctional diversity of the T cell receptor makes each T cell almost entirely unique. Therefore, it makes sense that T cells also display enormous phenotypic and functional diversity in both blood and tissues. This is particularly evident in the context of both infectious disease and cancer, where a great deal of heterogeneity is observed both within individual patient tumors and between patients.
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