Mesna (Uroprotective Agent): Mechanism, Uses & Side Effects | High-Yield Pharmacology | CanadaQBank

Mesna is a crucial uroprotective drug used to prevent hemorrhagic cystitis during chemotherapy. But do you know how it works and when to use it? In this high-yield pharmacology video, we break down Mesna’s mechanism of action, clinical uses, and potential side effects—plus real-life clinical vignettes to reinforce your knowledge.


What You’ll Learn in This Video:

What is Mesna? – Pharmacologic class and chemical structure
Mechanism of Action – How Mesna neutralizes acrolein (a toxic metabolite of cyclophosphamide & ifosfamide)
Clinical Uses – Preventing hemorrhagic cystitis during chemotherapy
Indications & Dosing – When and how to administer Mesna
Adverse Effects – Nausea, vomiting, allergic reactions
Drug Interactions – Considerations with alkylating agents
Clinical Vignettes – Test your knowledge with real-world applications

Ideal for:
Medical students, pharmacists, and healthcare professionals preparing for USMLE, MCCQE, PLAB, NCLEX, or any pharmacology-heavy exam.


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