Exploring the Tumor Microenvironment of Invasive Lobular Carcinoma With Jason Mouabbi, MD

In this interview from the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago, Oncology Data Advisor Editorial Board member Dr. Jason Mouabbi, Assistant Professor of Medicine at MD Anderson Cancer Center, discusses the poster he presented on “The Multiomic Tumor Environment Landscape of Invasive Lobular Carcinoma of the Breast,” including:

• The known role of the tumor microenvironment (TME) in invasive lobular carcinoma progression and therapeutic response
• The limitations of traditional histopathological methods in dissecting the complexity and heterogeneity of the TME
• His team’s approach using single-cell spatial phenotyping and multiplex immunofluorescence integrated with RNA sequencing to evaluate the TME
• How further evaluation of the TME with this approach can lead to the development of personalized therapeutic strategies for invasive lobular carcinoma
• And more!