Active Freeze Drying of pharmaceuticals

The Active Freeze Dryer (AFD) offers unique possibilities for producing sterile bulk pharmaceuticals in one processing step, always resulting in a fine loose powder which is directly available from the product collector.

Active Freeze Drying technology is especially suitable for pharmaceutical applications such as antibiotics, proteins, collagens and APIs. Material consistencies can range from solutions, dispersions to paste and even wet solids. The key benefits of this technology are efficiency, minimal handling and a consistent, high product quality.

Traditional tray-type freeze dryers are labour intensive. Hosokawa's Active Freeze Drying system eliminates this drawback and is a big step forward in the field of freeze drying thermo-sensitive bulk solids. Due to the agitated freeze drying process, different product characteristics can be improved without the need of post-processing steps.

Validation of their testing and manufacturing activities is a major challenge for pharmaceutical manufacturers, and the freeze drying process is no exception. Hosokawa Micron's Active Freeze Drying technique makes validation of pharmaceutical ingredients easier, faster and more cost effective by producing fully homogeneous batches of sterile material. André Hermsen, Manager Team Pharma at Hosokawa Micron, explains more.

More info: https://www.hosokawa-micron-bv.com/te...