The Lab Report Podcast #65 - The Multi-Omics Series Part 4: CBS and Transsulfuration - Sept 8, 2020
Автор: Genova Diagnostics
Загружено: 2025-10-16
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Multi-omics is the layering of genetic information (genomics) with laboratory biomarker results (metabolomics) to understand the root cause of disease and risk. This educational series focuses on genetic variants in specific enzymes and explains how to evaluate the systemic effects.
Today’s episode revolves around the enzyme cystathionine-beta-synthase (CBS). This enzyme is important for homocysteine metabolism, sitting at a branch point between two important cycles: methylation and transsulfuration. The action of this enzyme is important for balancing the critical functions of methylation with the creation of glutathione and energy. Listen to understand why this enzyme is important and what a genetic variant in CBS might mean for your patients.
“You’ve got to zoom out. You’ve got to look at all of the factors which regulate the CBS enzyme.” – Michael Chapman, ND
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