Valproic acid Vs Divalproex sodium (Depakote)

Divalproex sodium is a 1:1 combination of valproic acid and sodium valproate.

It is well known under the brand Depakote. It is available as extended release or delayed release tablets. It releases valproic acid in to the body that produces antiepileptic action. Divalproex is slowly absorbed in to the body and it produces consistent plasma levels. It has less gastric side effects compared with valproic acid alone. However, it has somewhat less bioavailability that the pure acid.

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