QC,ARD INTERVIEW QUESTIONS AND ANSWERS -VIDEO #12[2025] || Pharmaceutical Concept | PC [2025]

This Video explains about QC,ARD INTERVIEW QUESTIONS AND ANSWERS -VIDEO #12 Pharmaceutical concept || PC
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Preparing for a Quality Control (QC) or Analytical R&D (ARD) interview in the pharmaceutical industry? In this video, we cover the most commonly asked QC and ARD interview questions along with expert answers to help you succeed.

🔹 What’s Inside?
✅ Fundamental QC & ARD concepts
✅ Troubleshooting analytical techniques
✅ Regulatory compliance & method validation questions
✅ Real-world case studies & practical problem-solving

📌 Whether you're a fresh graduate or an experienced professional, this video will help you confidently tackle pharma job interviews.

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⌚️ TIME STAMP:
0:05 Contents of the video
1:06 1. What is the role of Internal Standards in Quantitative Analysis?
1:35 2. How do you determine the Number of Theoretical Plates (N) in HPLC?
2:06 3. What are the Different End-Capping Techniques in HPLC Columns?
2:37 4. What are the Causes of High Baseline Noise in HPLC/GC?
3:07 5. What are Common Gas Chromatography (GC) Carrier Gases?
3:38 6. What is the Difference Between Derivatization in HPLC vs. GC?
4:08 7. What are the Causes of Broad Peaks in HPLC?
5:03 8. What is the Principle of Mass Spectrometry (MS)?
5:33 9. What are the Regulatory Requirements for Analytical Instrument Qualification
6:03 10. How do you Handle Out-of-Specification (OOS) Results in an Analytical Lab?
7:04 11. What is the Difference Between QC and Analytical R&D?
8:04 12. How Do You Handle an Out-of-Trend (OOT) Result in Stability Testing?
8:35 13.What are the Different Dissolution Apparatuses Used in QC?
9:30 14. How Do You Determine the Robustness of an HPLC Method?
10.23 15. What are the Causes of High Backpressure in HPLC?
11:54 16. How Do You Identify a Ghost Peak in HPLC?
12:15 17. What is the Difference Between Signal-to-Noise (S/N) Ratio in LOD and LOQ?
12:47 18. What is the Difference Between KF Coulometric and KF Volumetric Titration?
13:19 19. What is the Significance of Peak Asymmetry (Tailing Factor) in HPLC?
13:46 20. What are the Common Causes of Column Void Formation in HPLC?
14:17 21. How Do You Perform Forced Degradation Studies?
15:09 22. How Do You Calculate the Relative Response Factor (RRF) for Impurity Quantification?
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