How Does CRISPR-Cas9 Work? Simple Explanation

CRISPR-Cas 9 works kinda like a military missile system. Cas-9 locks onto a target gene, then knocks it out. The gene will either stay cut, or is repaired via NHEJ or HDR.

Low key this is how scientists are going to genetically edit future X-men
#crispr #genediting #scifimadepossible

CRISPR = Clustered Regularly Interspaced Short Palindromic Repeats
PAM = Protospacer Adjacent Motif

gRNA = crRNA + tracrRNA

gRNA = guide RNA
crRNA = crispr RNA
tracrRNA= Trans-activating crispr RNA

NHEJ = Non-Homologous End Joining
HDR = Homology Directed Repair

Diagram made via BioRender