Hereditary Hyperbilirubinemias | Crigler-Najjar, Gilbert, Dubin-Johnson, Rotor |part 54

Master Hereditary Hyperbilirubinemias in this concise, exam-focused lecture for NRE-1 and USMLE Step 1.
We cover all high-yield bilirubin metabolism disorders, their genetics, enzyme defects, lab patterns, and key differentiating features.

Topics Covered:

Bilirubin metabolism overview

Unconjugated hyperbilirubinemias:

Gilbert Syndrome

Crigler-Najjar Syndrome Type I & Type II


Conjugated hyperbilirubinemias:

Dubin-Johnson Syndrome

Rotor Syndrome


Diagnostic clues (Step 1 favorites)

Mnemonics for easy recall

Clinical presentations & management pearls


Perfect for medical students preparing for NRE-1, USMLE Step 1, FCPS, PLAB, and med-school exams

hereditary hyperbilirubinemia, Crigler Najjar, Gilbert syndrome, Dubin Johnson, Rotor syndrome, bilirubin metabolism, liver disorders, unconjugated hyperbilirubinemia, conjugated hyperbilirubinemia, usmle gi, nre1 gastroenterology


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