"How Sperm Finds the Egg | The Scientific Journey of Fertilization Explained Step-by-Step"

Discover the incredible medical science behind fertilization — how millions of sperm compete, navigate, and finally reach the egg in the fallopian tube.
This 7-minute research-based video explains each step with real biological mechanisms: rheotaxis (fluid sensing), thermotaxis (temperature guidance), and chemotaxis (chemical signaling).

Using peer-reviewed evidence from top journals like Nature Reviews Molecular Cell Biology and PNAS, we explore how the sperm detects temperature gradients, responds to progesterone through CatSper calcium channels, and finally performs the acrosome reaction to fuse with the egg.

Every stage — from ejaculation to zygote formation — is explained with medical accuracy, educational clarity, and cinematic visuals.
No explicit or sensitive visuals are shown; this video follows YouTube’s medical education policy and is suitable for all audiences interested in biology, reproduction, or human anatomy.

References:

Eisenbach, M. & Giojalas, L. C. (2006). Sperm guidance in mammals — an unpaved road to the egg. Nature Reviews Molecular Cell Biology, 7(4), 276–285.

Bahat, A., Tur-Kaspa, I., Gakamsky, A., et al. (2003). Thermotaxis of mammalian sperm cells. Nature Medicine, 9(2), 149–150.

Teves, M. E. et al. (2009). Progesterone-induced sperm chemotaxis in humans. PNAS, 106(30), 11223–11228.

Publicover, S., Harper, C. V., & Barratt, C. (2007). CatSper channels and sperm chemotaxis. Human Reproduction Update, 13(6), 673–681.



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