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It is form of neurovascular headache in which neural events result in dilation of blood vessels aggravating the pain and resulting in further nerve activation.
Changes in the brainstem and its interactions with the trigeminal nerve, a major pain pathway, might be involved. So might imbalances in brain chemicals — including serotonin, which helps regulate pain in your nervous system.
while headache pain is caused by vasoconstriction (narrowing of the blood vessels). During a migraine, inflammation of the tissue surrounding the brain, i.e., neurogenic inflammation, exacerbates the pain.

Migraine triggers
There are a number of migraine triggers, including:

Hormonal changes in women. Fluctuations in estrogen, such as before or during menstrual periods, pregnancy and menopause, seem to trigger headaches in many women.

Hormonal medications, such as oral contraceptives and hormone replacement therapy, also can worsen migraines. Some women, however, find their migraines occurring less often when taking these medications.

Drinks. These include alcohol, especially wine, and too much caffeine, such as coffee.
Stress. Stress at work or home can cause migraines.

Sensory stimuli. Bright lights and sun glare can induce migraines, as can loud sounds. Strong smells — including perfume, paint thinner, secondhand smoke and others — trigger migraines in some people.

Sleep changes. Missing sleep, getting too much sleep or jet lag can trigger migraines in some people.

Physical factors. Intense physical exertion, including sexual activity, might provoke migraines.

Weather changes. A change of weather or barometric pressure can prompt a migraine.

Medications. Oral contraceptives and vasodilators, such as nitroglycerin, can aggravate migraines.

Foods. Aged cheeses and salty and processed foods might trigger migraines. So might skipping meals or fasting.

Food additives. These include the sweetener aspartame and the preservative monosodium glutamate (MSG), found in many foods.

Risk factors
Several factors make you more prone to having migraines, including:

Family history. If you have a family member with migraines, then you have a good chance of developing them too.
Age. Migraines can begin at any age, though the first often occurs during adolescence. Migraines tend to peak during your 30s, and gradually become less severe and less frequent in the following decades.
Sex. Women are three times more likely to have migraines.
Hormonal changes. For women who have migraines, headaches might begin just before or shortly after onset of menstruation. They might also change during pregnancy or menopause. Migraines generally improve after menopause.


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