换血疗法治疗新生儿黄疸的原理是怎样的 周熙惠 西安交通大学第一附属医院

换血疗法治疗新生儿黄疸的原理是怎样的 周熙惠 西安交通大学第一附属医院
对于重度的新生儿高胆红素血症采用换血治疗，会达到以下的几个效果：一、能够把血中的高浓度的胆红素置换出来，降低孩子发生胆红素脑病风险；第二、如果这个孩子是新生儿溶血病，通过换血治疗也可以很快的把大量致敏的红细胞置换出来。新生儿黄疸的换血治疗是一种有创的操作，要留置、穿刺股动脉或者是穿刺其他的外周动脉，另外还有几路的静脉输液要把新生儿血容量两倍的血输进去换出来，因此还是有相当大的风险。

What is the principle of exchange therapy for neonatal jaundice
For severe neonatal hyperbilirubinemia, blood exchange was used, It can achieve the following effects: first, it can replace the high concentration of bilirubin in the blood, Reduce the risk of bilirubin encephalopathy in children; Second, if the child is hemolytic disease of newborn, A large number of sensitized red blood cells can also be quickly replaced by exchange therapy. The exchange of blood for neonatal jaundice is an invasive operation, The femoral artery or other peripheral arteries should be retained or punctured, In addition, there are several ways of intravenous infusion to exchange the blood of the newborn with twice the blood volume, So there are still considerable risks.