My Thoughts on Gabapentin for Neuropathy | What to Know About Gabapentin!

Gabapentin for Nerve Pain. Gabapentin for Neuropathy. What You Need to Know About Gabapentin. Questions About Gabapentin. Gabapentin Side Effects.

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Timeline | Chapters
00:00 - Intro
0:26 - Off label Uses
1:02 - Not Much Compelling Evidence
1:41 - What's it Approved for?
2:18 - Neurontin Marketing Campaign
2:40 - NNT
3:10 - 10th Most Popular Med
4:19 - Cautions
4:40 - Misuse
4:49 - AAFP Message

What is Gabapentin Used for?

Gabapentin is a medication that is commonly used to treat neuropathic pain, seizures, and certain other conditions. However, individual responses to medications can vary, and not everyone may experience pain relief with gabapentin. There are several reasons why gabapentin might not be effective for pain relief in certain individuals.

Does Gabapentin Help With Nerve Pain?

Gabapentin is particularly effective for neuropathic pain conditions, such as diabetic neuropathy or postherpetic neuralgia. If the pain is not primarily neuropathic, gabapentin might not be the most suitable treatment. Accurate diagnosis of the underlying cause of pain is crucial for determining the most appropriate treatment plan.

Gabapentin Back Pain

There is limited evidence to support the use of either PG or GB in nonspecific CLBP. This review gathered eight trials looking at gabapentinoids for adults with long-term lower back pain. The evidence was very low quality, but overall, supports NICE guidance not to use these medicines to treat long-term lower back pain.

👉 https://journals.plos.org/plosmedicin...

What is Gabapentin For? What is Lyrica Good For?

Gabapentin and Lyrica, both sold by Pfizer, have been approved to treat only four debilitating pain problems: postherpetic neuralgia, diabetic neuropathy, fibromyalgia and spinal cord injury. Even for these approved uses, the evidence for relief offered by the drugs is hardly dramatic.

Neurontin vs Lyrica

Gabapentin was first approved by the U.S. Food and Drug Administration (FDA) for the treatment of seizures in 1993 and was subsequently approved for one pain indication, postherpetic neuralgia. Pregabalin was first marketed in 2004 and is currently FDA approved for the pain indications of diabetic neuropathy, postherpetic neuralgia, fibromyalgia, and pain associated with spinal cord injury.

Gabapentin for Sciatica

Among 209 patients with sciatica, Lyrica did not significantly reduce the intensity of leg pain when compared with a placebo, and dizziness was more commonly reported by the 108 patients who took the drug.

👉 https://www.nejm.org/doi/pdf/10.1056/...

Does Gabapentin Work?

If gabapentin does not provide adequate pain relief, it's crucial to communicate with a healthcare professional. They can reevaluate the diagnosis, adjust the treatment plan, consider alternative medications, or explore a multidisciplinary approach to pain management. It's not uncommon for healthcare providers to try different medications or combinations of therapies to find the most effective and tolerable solution for an individual's pain.

Gabapentin Taper

Abruptly discontinuing gabapentin without proper guidance can lead to withdrawal symptoms and potential health risks.

How Does Gabapentin Work for Pain?

The exact mechanism by which gabapentin works to alleviate nerve pain is not completely clear. It appears to prevent the heightened sensitivity to pain by regulating the release of neurotransmitters in the central nervous system.

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All content in this video and description including: information, opinions, content, references and links is for informational purposes only.