The Genetic Origins of Cancer

I’m sure you’ve known someone with cancer. It’s a frustrating disease that is as hard to research as it is to treat. Researchers at the Rockefeller University are using a rare pediatric liver cancer called Fibrolamellar to learn more about the genetic origins of cancer!



-To learn more about Fibrolamellar check out: https://www.fibroregistry.org/faq-fib... or http://www.fightfibrolamellar.org

-To learn more about CRISPR check out:    • Biologist Explains One Concept in 5 Levels...  


-Discussion on Fibrolamellar from Kastenhuber et al. “DNAJB1–PRKACA fusion kinase interacts with β-catenin and the liver regenerative response to drive fibrolamellar hepatocellular carcinoma” PNAS (2017). http://www.pnas.org/content/early/201...


-Cancer death numbers from https://www.cancer.gov/about-cancer/u...


-Previous research on DNAJB1–PRKACA chimera from Honeyman and Simon et al “Detection of a Recurrent DNAJB1-PRKACA Chimeric Transcript in Fibrolamellar Hepatocellular Carcinoma” Science (2014). http://science.sciencemag.org/content...





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