This group usually regulates cell division, cell cycle, growth, and apoptosis as their normal
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Загружено: 2025-05-27
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This group usually regulates cell division, cell cycle, growth, and apoptosis as their normal function. It is therefore logical to see how they could cause cancer when mutated.
Proto-oncogenes are a group of genes that play a crucial role in regulating cell division, cell cycle, growth, and apoptosis, which is the process of programmed cell death. Normally, these genes help to promote cell growth and proliferation, but when they are mutated or overexpressed, they can become oncogenic, leading to uncontrolled cell growth and cancer. The mutation of proto-oncogenes can disrupt the normal balance of cell growth and division, allowing damaged cells to survive and proliferate, which can ultimately lead to the development of tumors. The study of proto-oncogenes is closely related to our understanding of cancer biology and the development of targeted therapies that aim to inhibit the activity of these mutated genes. Furthermore, research on proto-oncogenes has broader implications for our understanding of cellular signaling pathways and the complex interactions between genes and environmental factors that contribute to cancer development.
Textbook sections that may cover this topic include chapters on cell biology, genetics, and cancer biology in general biology or biochemistry textbooks, such as Campbell Biology (Chapters 12 and 18), Molecular Biology of the Cell (Chapters 20 and 24), or Lehninger Principles of Biochemistry (Chapters 23 and 25). This subject is typically covered in introductory biology or biochemistry courses, and related topics may include signal transduction pathways, gene regulation, and the molecular mechanisms of cancer. Other relevant chapters may discuss the role of tumor suppressor genes, DNA repair mechanisms, and the cellular responses to stress and damage, all of which are important for understanding the complex processes that contribute to cancer development.
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