How to Identify Molecules - Proton NMR: Crash Course Organic Chemistry #26

If you were given a chemical and told to identify it, how would you go about doing that? You could look at different factors like color, boiling point, melting point, or smell, but the answer still might not be clear. Thankfully, today we have a more precise, higher-tech way of identifying chemicals called Nuclear Magnetic Resonance, or NMR. In this episode of Crash Course Organic Chemistry, we’ll look at how NMR allows us to visualize a molecule as a spectrum, and what the peaks on the spectrum tell us about the structure of the molecule.

Episode Sources:
Mahdi, J. G. (2010). Medicinal potential of willow: A chemical perspective of aspirin discovery. Journal of Saudi Chemical Society, 14(3), 317-322.
Dempsey, D.A., Klessig, D.F. How does the multifaceted plant hormone salicylic acid combat disease in plants and are similar mechanisms utilized in humans?. BMC Biol 15, 23 (2017). https://doi.org/10.1186/s12915-017-03...
Still, W. C., Kahn, M., & Mitra, A. (1978). Rapid chromatographic technique for preparative separations with moderate resolution. The Journal of Organic Chemistry, 43(14), 2923-2925.
Pastre, J. C., & Duarte Correia, C. R. (2006). Efficient Heck arylations of cyclic and acyclic acrylate derivatives using arenediazonium tetrafluoroborates. A new synthesis of the antidepressant drug (±)-Paroxetine. Organic letters, 8(8), 1657-1660.

Series Sources:
Brown, W. H., Iverson, B. L., Ansyln, E. V., Foote, C., Organic Chemistry; 8th ed.; Cengage Learning, Boston, 2018.
Bruice, P. Y., Organic Chemistry, 7th ed.; Pearson Education, Inc., United States, 2014.
Clayden, J., Greeves, N., Warren., S., Organic Chemistry, 2nd ed.; Oxford University Press, New York, 2012.
Jones Jr., M.; Fleming, S. A., Organic Chemistry, 5th ed.; W. W. Norton & Company, New York, 2014.
Klein., D., Organic Chemistry; 1st ed.; John Wiley & Sons, United States, 2012.
Louden M., Organic Chemistry; 5th ed.; Roberts and Company Publishers, Colorado, 2009.
McMurry, J., Organic Chemistry, 9th ed.; Cengage Learning, Boston, 2016.
Smith, J. G., Organic chemistry; 6th ed.; McGraw-Hill Education, New York, 2020.
Wade., L. G., Organic Chemistry; 8th ed.; Pearson Education, Inc., United States, 2013.

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