Diffuse Large B-Cell Lymphoma | Part 2: Treatment | R-CHOP, O-CHOP, DA-EPOCH-R, Pola-R-CHP, CAR-T
Автор: Tom Fusillo, DO
Загружено: 2025-01-28
Просмотров: 644
Cancer therapies are constantly changing and can be difficult to get a firm grasp of the many options. In this video I explain the primary therapies used to treat diffuse large b-cell lymphoma (DLBCL). We first discuss the NCCN recommend treatment algorithm. Then we go into some of the specific therapies and regimens used, including R-CHOP, O-CHOP, DA-EPOCH-R, Pola-R-CHP, RICE, MATRIX, and CAR-T.
This video is intended to be at the level of a internal medicine resident.
Twitter/X: https://x.com/T_Fus/
#lymphoma #cancertherapy #moleculargenetics #hematology #oncology
00:00 Introduction
00:39 Treatment Flowchart
03:16 Overview of Therapies
04:00 R-CHOP
07:43 O-CHOP
09:13 DA-EPOCH-R
12:13 Pola-R-CHP
14:17 CNS Prophylaxis
16:18 CNS Therapy
17:50 CAR-T Therapy
20:06 Outro
References:
https://www.nejm.org/doi/10.1056/NEJM...
https://ashpublications.org/blood/art...
https://ashpublications.org/blood/art...
https://ashpublications.org/blood/art...
https://ascopubs.org/doi/10.1200/JCO....
https://ascopubs.org/doi/full/10.1200...
https://pubmed.ncbi.nlm.nih.gov/30501...
https://ashpublications.org/blood/art...
https://ascopubs.org/action/downloadS...
https://www.nejm.org/doi/full/10.1056...
https://ashpublications.org/thehemato...
https://ashpublications.org/blood/art...
https://www.nature.com/articles/bjc20...
https://haematologica.org/article/vie...
https://www.sciencedirect.com/science...
https://ashpublications.org/blood/art...
https://www.nejm.org/doi/full/10.1056...
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