Spravato vs Antidepressants: Which is Better & Why?

If you’ve tried antidepressants and still feel stuck, you’re not alone. Many people wonder if Spravato (esketamine) could work better than daily SSRIs or SNRIs—and why it’s so different.

In this clear, step-by-step video, we break down:

💊 Antidepressants vs Spravato: How they work in the brain (and why Spravato is faster).
🧠 Brain Reset Explained: Why Spravato targets glutamate, not serotonin, and rewires your brain.
⏱️ Why Pills Can Take Weeks: And how Spravato can improve symptoms in hours.
😴 Side Effects Compared: Emotional numbness vs dissociation—what’s the real difference?
📅 Treatment Plans: Daily pills vs weekly in-clinic sessions—what fits your lifestyle?
✨ Real Results: Who benefits from Spravato most, and why it’s FDA-approved for treatment-resistant depression.
🔍 What Doctors Say: When to switch from SSRIs to Spravato (or combine them safely).

Whether you’re frustrated with traditional meds or simply exploring your options, this video explains exactly why Spravato is making headlines as a new generation depression treatment.

This video provides an in-depth comparison of Spravato (esketamine) versus traditional SSRI antidepressants. To make the video accessible, here are the key chapters written simply and using the M:SS format:

⏱️ Video Chapters

0:00 Intro: Are SSRIs Still the Best?
0:45 SSRIs: What They Do (And Why It's Not Enough)
1:30 Why We Use More Pills But Get Worse
2:25 Problem 1: Antidepressants Are Slow
2:48 Problem 2: Pills Fail Most People
2:54 Problem 3: The Side Effects of Pills
3:13 Problem 4: Exercise Can Be More Powerful
3:26 The New Options in Mental Health
4:10 What is Spravato? (The FDA Breakthrough)
4:37 Spravato's Target: Glutamate (The Neuroplasticity Secret)
5:14 Science: Spravato vs. Pills (The Big Difference)
6:05 Proof 1: Spravato Works Faster (Transform 2 Study)
6:40 Proof 2: Spravato Stops Relapse (Sustain 1 Study)
7:40 Proof 3: Spravato vs. Quetiapine (Escape TRD Study)
8:25 Proof 4: Spravato Works Alone (Monotherapy)
9:00 Why Spravato is the VIP at the Party
9:58 What Real Patients Say (Reading Reddit Comments)
11:37 Patient Outcomes: Emotions are Clearer
13:35 The Final Question: Which is Better?
14:50 When to Use Spravato (Final Recommendation)
15:04 Connect & Close


✅ About Marpa Minds
Marpa Minds is a next-generation mental health network offering FDA-approved Spravato (esketamine) and ketamine therapy for depression, trauma, and emotional numbness.

👉 Learn more or book a consult: www.marpaminds.com

🔗 Follow Us:
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LinkedIn:   / marpa-minds  

📌 If you’re ready to move beyond pills that only mask symptoms, this is your guide to what’s next.

#Spravato #Antidepressants #MentalHealth #DepressionTreatment #MarpaMinds