Budd–Chiari Syndrome & Portal Vein Thrombosis | USMLE Step 1 & NRE1 High-Yield Review|part 46

Master Budd–Chiari Syndrome and Portal Vein Thrombosis (PVT) in one high-yield, exam-focused video for USMLE Step 1 and NRE 1.
This lecture explains causes, pathophysiology, clinical features, diagnosis, and treatment exactly as outlined in First Aid—clear, rapid-revision style.

Budd–Chiari Syndrome
– Hepatic vein thrombosis → hepatic congestion
– Causes: hypercoagulable states (Polycythemia vera, pregnancy, OCPs), myeloproliferative disorders
– Symptoms: RUQ pain, hepatomegaly, ascites
– Diagnosis: Doppler ultrasound
– Treatment: anticoagulation, TIPS, liver transplant (severe)

Portal Vein Thrombosis (PVT)
– Obstruction of portal vein → portal hypertension WITHOUT liver failure
– Causes: cirrhosis, malignancy, hypercoagulability, abdominal infections
– Symptoms: splenomegaly, varices, abdominal pain
– Diagnosis: Doppler ultrasound / CT
– Treatment: anticoagulation, manage varices, treat underlying cause

Perfect for medical students, residents, USMLE/NRE candidates, and fast revision.



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