Enzymes: Mr. W's Enzyme Song

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SUMMARY: This movie explains the biology of enzymes. Enzymes are protein catalysts that accelerate chemical reactions by lowering activation energy, playing a crucial role in processes like digestion and metabolism in all organisms. They bind to substrates at their active site, facilitating the transformation of reactants into products, and their function depends on factors like pH and temperature. However, changes in these environmental conditions can denature enzymes, reducing or destroying their activity, making them essential but sensitive players in biological systems.

My hope is that this video will catalyze lots of learning.

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Enzymes LYRICS:
They're the protein catalysts in every organism
ENZYMES!
Through enzymatic action your metabolism's driven
ENZYMES!
In staphylococcus, jellyfish, tarantulas and trees,
They lower activation energy
Enzymes, in you and me now
ENZYMES!

You got 'em in your cells where they do cellular digestion,
ENZYMES!
You got 'em in your mouth and in your stomach and intestines
ENZYMES!
The thing an enzyme acts upon is called a substrate.
They fit like lock and key with complementary shape
Enzymes, speed up reaction rates
ENZYMES!

An enzyme binds its substrate at its active site
ENZYMES!
Bound together in a complex where they snuggle so tight,
ENZYMES!
New bonds will form and break due to the active site's chemistry
Reactants become products, it's the enzyme's specialty,
Product gets release enzyme repeats its action readily
ENZYMES!

Like any molecule an enzyme's shape defines its function.
ENZYMES!
Environmental change that changes shape leads to malfunction,
ENZYMES!
Every enzyme has a pH where it catalyzes best,
a pH change will set enzyme activity to rest.
Enzymes are so sensitive they're easily upset
ENZYMES!

More heat until a certain point increases their efficiency
ENZYMES!
But too much heat denatures them destroying their activity
ENZYMES!
That's why a fever running high's a dangerous situation,
All that heat can alter enzymatic conformation.
Keep it 98.6 for enzyme optimization
ENZYMES!

Enzymes in saliva will break starch into glucose
ENZYMES!
If you lack the enzyme lactase then you won't enjoy milk lactose,
ENZYMES!
Tay-sachs, galactosemia and PKU disease,
All caused by inherited enzyme deficiencies
ENZYMES, they're what everybody needs
ENZYMES!