Physiology of Thyroid Hormones: Synthesis, Secretion, and Function

A concise, high-yield overview of thyroid hormone physiology, including synthesis, secretion, and major functions. Covers the synthesis of T3 and T4: iodide uptake by the thyroid, oxidation to iodine, organification of tyrosine residues on thyroglobulin, coupling reactions to form T3 and T4, storage in colloid, and release into circulation under TSH regulation. Explains secretion dynamics, including the conversion of T4 to the active T3 in peripheral tissues. Highlights key physiological roles: regulation of basal metabolic rate, growth and development, cardiovascular function, nervous system maturation, thermogenesis, and reproductive system effects. Perfect for MBBS, USMLE, and endocrine physiology revision.
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