Season 4, Episode 8 (Isotretinoin for SD, Iron Therapy, Memantine for TTM, Antifungal Resistance)

The Evidence Based Hair Podcast was created by dermatologist & hair loss specialist Dr Jeff Donovan to highlight new, hot off the press, world-class research in the field of hair loss. The podcast was created for hair loss practitioners around the world who care for patients with all different types of hair loss. Each week, different hair loss research topics are covered in the podcast including new research related to androgenetic alopecia, alopecia areatea, telogen effluvium, traction alopecia, tinea capitis, trichotillomania, chemotherapy induced hair loss, lichen planopilaris, frontal fibrosing alopecia, dissecting cellulitis, folliculitis decalvans, discoid lupus, central centrifugal cicatricial alopecia, erosive pustular dermatosis.... and a whole lot more.

TOPICS COVERED IN THIS WEEK'S PODCAST:

ISOTRETINOIN FOR TREATING SEBORRHEIC DERMATITIS

Yanfei Z et al (starts at 10:56). Efficacy and safety of oral isotretinoin in the treatment of moderate to severe seborrheic dermatitis: a retrospective study. Int J Dermatol. 2023 Feb 15.

Geissler SE et al (starts at 16:17). Very low dose isotretinoin is effective in controlling seborrhea. J Dtsch Dermatol Ges. 2003 Dec;1(12):952-8.

Rademaker M (starts at 17:38). Low-Dose Isotretinoin for Seborrhoeic Dermatitis. J Cutan Med Surg. 2017 Mar/Apr;21(2):170-171

IRON SUPPLEMENTATION FOR IRON DEFICIENCY ANEMIA

Jongkraijakra S et al (starts at 21:47). A randomized controlled trial of thrice-weekly versus thrice-daily oral ferrous fumarate treatment in adult patients with iron-deficiency anemia. Ann Hematol. 2023 Apr 3;1-8.

Stoffel NU et al (starts at 29:03). Iron absorption from oral iron supplements given on consecutive versus alternate days and as single morning doses versus twice-daily split dosing in iron-depleted women: two open-label, randomised controlled trials. Lancet Haematol. 2017 Nov;4(11):e524-e533.

Mehta S et al (starts at 30:59). A Prospective, Randomized, Interventional Study of Oral Iron Supplementation Comparing Daily Dose with Alternate Day Regimen Using Hepcidin as a Biomarker in Iron Deficiency Anemia. J Assoc Physicians India. 2020 May;68(5):39-41.

Kaynar LA et al (starts at 31:34). Comparison of daily oral iron replacement therapy with every other day treatment in female reproductive age patients with iron-deficiency anemia. Ann Hematol. 2022 Apr 23.

MEMANTINE FOR TREATING TRICHOTILLOMANIA

Grant JE et al (starts at 38:52). Double-Blind Placebo-Controlled Study of Memantine in Trichotillomania and Skin-Picking Disorder. Am J Psychiatry. 2023 Feb 22;appiajp20220737.

EPIDEMIOLOGY OF TINEA CAPITIS IN THE UNITED STATES
Gold, JA et al (starts at 44:28). Epidemiology of tinea capitis causative species: an analysis of fungal culture results from a major U.S. national commercial laboratory. J Am Acad Dermatol. 2023 Mar 30;S0190-9622(23)00526-1.

Gold, JA et al. Inadequate diagnostic testing and systemic antifungal prescribing for tinea capitis in an observational cohort study of 3.9 million children, United States. J Am Acad Dermatol. 2023 Feb 15;S0190-9622(23)00189-5.

DERMATOPHYTE ASSOCIATED ANTIFUNGAL RESISTANCE

Zeesha F et al (starts at 49:11). The rising menace of antifungal resistance in dermatophytes among the patients of tinea capitis. J Pak Med Assoc. 2023 Jan;73(1):43-48.

Mukherjee, P.K. et al (starts at 56:06). Clinical Trichophyton rubrum strain exhibiting primary resistance to terbinafine. Antimicrob. Agents Chemother. 2003, 47, 82–86.

Favre, B (starts at 57:06). Biochemical characterization of terbinafine-resistant Trichophyton rubrum isolates. Med. Mycol. 2004, 42, 525–529.

Singh, A (starts at 58:09). High terbinafine resistance in Trichophyton interdigitale isolates in Delhi, India harbouring mutations in the squalene epoxidase gene. Mycoses 2018, 61, 477–484.

Ebert, A et al (starts at 58:28). Alarming India-wide phenomenon of antifungal resistance in dermatophytes: A multicentre study. Mycoses 2020, 63, 717–728.

Ayodele EH et al (starts at 1:04:08). PREVALENCE, IDENTIFICATION AND ANTIFUNGAL SUSCEPTIBILITY OF DERMATOPHYTES CAUSING TINEA CAPITIS IN A LOCALITY OF NORTH CENTRAL NIGERIA. Afr J Infect Dis. 2020 Dec 14;15(1):1-9.