Flatworms could reduce reliance on rats and mice in early-stage drug testing of antipsychotic drugs
Автор: Connecting Research | University of Reading
Загружено: 2025-08-26
Просмотров: 123
Professor Vitaliy Khutoryanskiy (Professor of Formulation Science at Reading School of Pharmacy) introduces a new study which found that planaria - harmless flatworms found in ponds and rivers - react to brain medicines in ways similar to rodents. This adds to a growing body of evidence that tiny flatworms can
be used to reduce the number of experiments on more complex animals, aligning with ethical guidelines.
Read the study:
Xiong, Y., Shankland, K. & Khutoryanskiy, V.V. Cyclodextrin-mediated Enhancement of Haloperidol Solubility: Physicochemical Studies and In Vivo Investigation Using Planaria Worms. Pharm Res (2025). https://doi.org/10.1007/s11095-025-03...
Learn about the research centre and lab:
Physicochemical, Ex Vivo and Invertebrates Tests and Analysis Centre (PEVITAC), https://pevitac.co.uk/
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