Engineering Complex Antigens: Major Histocompatibility Complexes & Multipass Transmembrane Proteins
Автор: Gator Bio
Загружено: 2024-07-15
Просмотров: 446
In support of the biopharmaceutical sector’s efforts to innovate therapeutic solutions against debilitating diseases, we have developed two vital complex antigens tailored to meet the industry’s pressing demands. Our innovative work includes the development of versatile MHC molecules, enabling rapid peptide loading in TCR-T cell therapy research applications, thus providing researchers with unparalleled ease of use. Furthermore, our expansion of the GPCR catalog now encompasses offerings in both VLP and nanodisc formats. Notably, our nanodiscs differ from conventional methods by avoiding the use of detergent in their extraction process.
In this webinar, we discussed how Gator Biolayer Interferometry was used for binding kinetics studies of GPCR/VLP and GPCR nanodiscs.
Recorded on July 11, 2024
0:00 Introduction
1:43 Introduction of Gator Bio technology - Hongshan Li
13:39 Engineering of complex antigens - Manhee Suh
14:52 About Kactus
17:51 Major histocompatibility complexes
33:29 Multipass transmembrane proteins
55:16 Q&A session
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