The Potential of Psychedelics for the Treatment of Neuropsychiatric Disorders

There is renewed interest in developing psychedelics such as psilocybin, LSD, or MDMA as potential treatments for mental health disorders, including major depression, post-traumatic stress disorder, and anxiety. This presentation will explain the different types of psychedelics that are being investigated as potential drugs, provide an overview of their long history of use, and present current efforts to bring these potential drugs to the clinic with an emphasis on the pharmacology and current understanding of the mode of action as well as the ADME properties of these compounds. Lastly, we will briefly touch on potential challenges.

Key concepts discussed in this webinar include:
• An overview of psychedelics
• Pharmacology, mode of action, and ADME properties
• Development of the next generation of psychedelics
• Clinical trials
• Challenges for psychedelic drug development

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About the Presenter
Dr. Tina Mueller is a Scientific Advisor for ADME-Tox Services at BioIVT. She joined BioIVT in 2023 and consults with customers and internal teams on in vitro ADME programs with a focus on in vitro DDI studies and compliance with regulatory guidelines. Tina obtained her PhD in Biochemistry and Microbiology and earned a Master’s in Environmental Sciences from the Swiss Federal Institute of Technology in Zurich, Switzerland. Before joining BioIVT, she was an Associate Director, Research at Cybin, a small biotech company developing new mental health therapeutics based on psychedelics, where she led the company’s research programs from early through late discovery. Additionally, Dr. Mueller served as a Research Associate Professor at Michigan State University, Senior Staff Scientist at Scripps Florida, and Professor for Biomedical Sciences at Keiser University.