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3. Phylogenetic analysis of pathogens (lecture - part3)
Автор: The Roslin Institute - Training
Загружено: 2015-06-10
Просмотров: 5891
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Lecture by professor Ross Fitzgerald, filmed at The Roslin Institute, March 2015.
(Recommended YouTube playback settings for the best viewing experience: 1080p HD)
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Content:
a. MLST(Multi Locus Sequence Typing)
--Comparable between laboratories, unambiguous
--Gold standard for S. aureus ? over 1400 ST identified to date
b. Staphylococcus aureus has a clonal population structure
--Population structure is largely host-adapted
--6 major human associated MRSA clonal complexes
c. Ancient human to animal host jumps by S. aureus strains resulted in livestock-endemic clones
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