The Dangerous Loop of Opioids: Tolerance, Pain, and the Brain

In Part 5 of our Pain Series, we dive deep into the neuroscience of opioid receptor activation and how it leads to tolerance, dependence, and addiction. If you've ever wondered how opioids affect the body and brain over time, this is your comprehensive guide.

👉 Topics Covered in This Video:

🧠 The structure and function of opioid receptors (μ, δ, κ)
🔬 Role of second messenger systems in opioid signaling
⚡ Immediate receptor desensitization after opioid exposure
🔄 How tolerance develops and why it varies between systems
😩 Understanding dependence and withdrawal symptoms
📘 Diagnostic criteria from DSM-4 and DSM-5 for opioid use disorder
🧬 Intracellular adaptation and long-term signaling changes
🧰 System-level counteradaptation mechanisms

👉 Don’t forget to like, comment, and subscribe for more episodes in this series on pain and neuroscience.

If you like to earn CMES fro this course, go to the following course link on DrBeen.com: https://members.drbeen.com/courses/pa...

🌐 [DrBeen's Website] (https://members.drbeen.com/courses)
📘 [DrBeen on Facebook] (  / drmobeensyed  )
📸 [Follow us on Instagram] (  / drbeen_medical  )

🔗 Also, check out our other YouTube channel for additional valuable content: [DrBeen Medical Lectures] (   / @drbeenmedicallectures  )

🙌 Thank you for choosing DrBeen Medical Lectures as your trusted source for advancing your medical knowledge. Together, let's foster a community of continuous learning and excellence in healthcare! 💙

🛑 Medical Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health-related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.

#DrBeenMedical #MedicalEducation #HealthcareProfessionals #ContinuousLearning #MedEd #MedicalLectures #StayCuriousStayInformed #neuropathicpain #CRPSsymptoms #Paraesthesia #painpathways #opioidreceptors #opioidtolerance #biology #painmanagement #opioid #doctor #neuroscience #opioidpharmacology #painrelief