Why phenibut and other "under the radar" drugs are worrying

We’ve talked a lot about gabapentin over the years—its uses, misuses, and what it could eventually lead to. But there’s a new kid on the block—phenibut (beta-phenyl-gamma-aminobutyric acid).

Phenibut is a neuropsychotropic drug discovered and introduced into clinical practice in Russia in the 1960s. It is not legal in the US because it was never considered worthy of the FDA’s consideration. However, since the US has the largest market for illicit drugs, phenibut is here to contend with. Phenibut has anxiolytic activity with neurotropic effects, which means it enhances cognition and produces a euphoric effect.

In this episode of Medical History Mysteries, we’ll talk about drugs that fly under the radar—such as phenibut, nitazenes, tianeptine (gas station heroin), and others—and how they can affect your patients and ultimately their dental care.

Thumbnail images credit: AndreyPopov / iStock / Getty Images Plus

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About Dr. Pamela Maragliano-Muniz

Pamela Maragliano-Muniz, DMD, is the chief editor of Dental Economics. Based in Salem, Massachusetts, Dr. Maragliano-Muniz began her clinical career as a dental hygienist. She went on to attend Tufts University School of Dental Medicine, where she earned her doctorate in dental medicine. She then attended the University of California, Los Angeles, School of Dental Medicine, where she became board-certified in prosthodontics. Dr. Maragliano-Muniz owns a private practice, Salem Dental Arts, and lectures on a variety of clinical topics.

About Tom Viola, RPh, CCP

With more than 30 years’ experience as a board-certified pharmacist, clinical educator, professional speaker, and published author, Tom Viola, RPh, CCP, has earned the reputation as the go-to specialist for making pharmacology practical and useful for dental teams. He is the founder of Pharmacology Declassified and is a member of the faculty of more than 10 dental professional degree programs. Viola has contributed to several professional journals and pharmacology textbooks, and currently serves as a consultant to the American Dental Association’s Council on Scientific Affairs.

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Our videos are for informational purposes only and do not provide a comprehensive education on any topic, nor do they provide any medical advice for any patient or medical/dental professional that provides patient care. Seek recommendations from your medical professional for any personal medical care.