Can Aspirin Cause Psychosis?

Can Aspirin Cause Psychosis?

This lecture takes a look at the relationship between non-steroidal anti-inflammatory drugs (NSAIDs) and psychiatric symptoms.

The primary, immediate biochemical effect of NSAIDs is to inhibit the production of prostaglandin signaling molecules.

The prostaglandins have a wide range of biological effects. Among them is the regulation of dopamine release.

For some people, it seems, NSAID medications may function as pro-dopamine drugs. This may explain some of the psychiatric adverse effects of the NSAIDs.

This lecture was given at the January 5, 2021 meeting of the SZconsult learning community.

SZconsult is a free consultation + education service offered by Northeast Ohio Medical University. It’s open to any clinician who wants to learn more about schizophrenia-spectrum illness, or who wants to tap into the collective wisdom of the learning community to find answers to clinical problems.

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