Webinar: Fundamentals of Spray-Dried Dispersion Technology
Автор: Capsugel
Загружено: 2015-03-24
Просмотров: 8458
Current estimates indicate that more than 70% of new chemical entities require solubilization technology to achieve efficacious plasma exposure. Amorphous solid dispersion technology is a leading approach to improve solubility and dissolution rate of these insoluble compounds by providing a supersaturated concentration of drug in the gastrointestinal environment, which often translates to rapid absorption and improved bioavailability. Amorphous solid dispersions are typically prepared by using hot-melt extrusion or spray drying processes. This webinar will focus on the fundamentals of formulating and processing of spray-dried dispersions, including stability assessment, in-vitro performance, and downstream manufacturability.
Key Learning Objectives
• Develop an appreciation of key factors leading to the use of spray-dried dispersion technology
• Understand the advantages and range of spray-dried dispersions and spray drying technology
• Learn the fundamentals of spray-dried dispersion formulation selection, process development, and scale-up
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