CACA Webinar New LC Particle Technology Oligonucleotide Separations Part 2

This webinar is the 2nd part of our series on monodisperse fully porous particles, presented by Geoff Faden. The research and data presented was done in collaboration with Sylwia Kowalska and Szymon Bocian at Nicolaus Copernicus University in Poland.
In this work, we discussed how utilizing monodisperse fully porous particle technology (MFPP) generates significantly higher resolution as compared to polydisperse particle technology, due to compressing the λ value of the chromatographic packed bed. We apply this new technology to oligonucleotide analyses. Applying a novel bonded phase chemistry to the monodisperse silica particle architecture and packing these particles in a chemically inert coated hardware allows significant advantages for oligonucleotide separations. For single stranded oligonucleotide species, we can demonstrate comparable resolution to industry standard ion-pair additive separations without ion-pair based mobile phases.

Geoff Faden is the President and CEO of MAC-MOD Analytical. He received his Bachelor of Science in Chemistry from Pennsylvania State University in 2003 and his MBA from Temple University in 2014. He has served as a trusted chromatography partner for the life science industry for over 15 years, and has experience working with major pharmaceutical, biopharmaceutical, industrial chemical, and environmental companies to improve their workflow.